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Patient portrayal of a man and woman walking among some trees

ALPROLIX® Patient Support

HemAssist provides the access, education, and ongoing support you need from Sanofi for your hemophilia B journey.

Start your journey with support from HemAssist

Once you’ve been prescribed ALPROLIX, you can enroll in HemAssist to get the support you need to start and stay with treatment. We offer financial assistance to eligible patients, help you navigate insurance, and provide supplemental infusion training. After you enroll, your HemAssist team will call you within 24 hours to welcome you to the program and explain what to expect. Save 1-833-723-5463 to your contacts. Learn how to enroll

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OUR SUPPORT

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Affording ALPROLIX

No matter your situation, we are committed to helping you access and afford treatment. Your team will verify your insurance coverage and determine what financial assistance programs you may be eligible for.

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Starting treatment

Your team can help you get started with ALPROLIX right away. We offer supplemental infusion training, make sure you receive medication, and offer tips to help you build a treatment routine.

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Ongoing support

Our team provides support and guidance throughout your ALPROLIX journey. This includes helping you maintain motivation to stay with your treatment as prescribed, navigate new insurance, and more.

Financial assistance

Regardless of your insurance status, our team is here to help. If you need help paying for medication, we can help determine if you may be eligible for financial assistance.

Copay Assistance Program*

If you have commercial insurance (insurance sponsored by your employer or private insurance) and you’re having trouble paying for ALPROLIX, HemAssist's Copay Assistance Program may be able to help. Get ALPROLIX for as little as $0.

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Free Trial Program†

Patients prescribed ALPROLIX for the first time can receive their first 30-day supply of treatment generally within 24 to 48 hours with a valid prescription from their healthcare provider through the Free Trial Program†. While you and your healthcare provider are deciding what treatment is right for you, a dedicated HemAssist Case Manager will review your health insurance information and coverage for your prescribed medication. Once the enrollment is complete, your Case Manager will contact you within 24 hours with next steps.

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Patient Assistance Program†

HemAssist’s Patient Assistance Program may be available to help eligible ALPROLIX patients who are uninsured, underinsured, or experiencing a temporary loss in insurance coverage.

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* Not valid if the patient is utilizing a state or federally funded health insurance program such as Medicare (including Medicare Part D), Medicaid, Medigap, VA, DoD, TRICARE®, state pharmaceutical assistance program, etc. to pay in part or in full for their ALPROLIX prescription. Not valid where prohibited by law. Sanofi reserves the right to modify or terminate the Copay Program at any time without notice. Savings by patients may vary depending on their out-of-pocket costs. The program is intended to help patients afford their ALPROLIX prescription. Patients may have insurance plans that attempt to dilute the impact of the assistance available under the program. In those situations, the program may change its terms.

† Free Trial valid only for a patient’s first prescriptions and it is limited to one use per patient per product for their lifetime. Free Trial not valid in Vermont. Claims for free products dispensed through the Free Trial or Patient Assistance Programs shall not be submitted to any third-party payer, public or private (e.g. private insurance, Medicaid, Medicare, VA, DoD, TRICARE®, or similar federal or state programs) for reimbursement. All Programs not valid where prohibited by law. Sanofi reserves the right to modify or terminate the Programs at any time without notice. Program details provided upon registration.

Have questions?

Our team is here to assist you.

Call 1-833-723-5463 Monday - Friday 8 AM to 7 PM ET.

Meet your team
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Getting started on ALPROLIX

Once you've enrolled, your Case Manager will call to welcome you to HemAssist within 24 hours. They will conduct an insurance investigation to understand your coverage. If you have questions about getting started with ALPROLIX, including supplemental infusion support, reach out to HemAssist to connect with your Clinical Educator. Call 1-833-723-4563 Monday - Friday 8 AM to 7 PM. You can also get started with the resources below.

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RESOURCES FOR STARTING ALPROLIX

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Helpful downloads

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Reconstitution & administration video

Support along the way

Starting a new treatment may come with a lot to learn. That’s why, from the moment you enroll, you have a dedicated HemAssist team with support on your side. From digital resources to personalized check-ins, HemAssist is here to help you get started with confidence. Learn more about your team below and enroll to get started with support.

MEET YOUR TEAM

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Clinical Educator (CE)

Your Clinical Educator is your point of contact for ALPROLIX education, tips, supplemental infusion training, and ongoing support.

Your Clinical Educator will not provide personal medical advice. For all questions about your individual health needs, consult with your treating physician.

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Case Manager

Your Case Manager assists with navigating insurance coverage and identifying the financial support you may be eligible for.

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Community Relations and Education Manager (CoRe)

CoRes are dedicated to providing education and empowering those within the hemophilia community through one-to-one communication, as well as through community events and conferences.

REASONS TO REACH OUT

Your Clinical Educator and Case Manager are available to assist you at any point along your ALPROLIX journey.

Your Clinical Educator can provide supplemental infusion training support along with helpful tips about building a treatment routine. Call 1-833-723-5463 Monday – Friday 8 AM to 7 PM ET.

When you change or start new insurance, you may have questions about affording ALPROLIX. Contact your Case Manager for help navigating the process. Call 1-833-723-5463 Monday – Friday 8 AM to 7 PM ET.

These are important milestones not only in adulthood, but also in treatment responsibility. Your team can help you navigate life changes such as going to college, starting a new job, or choosing insurance for the first time. Call 1-833-723-5463 Monday – Friday 8 AM to 7 PM ET.

Starting and staying with a new treatment takes dedication. Your Clinical Educator can help with tips for infusion day, building your treatment routine, and help maintaining motivation when you need it. Call 1-833-723-5463 Monday – Friday 8 AM to 7 PM ET.

Resources from the community

National Bleeding Disorders Foundation logo

National Bleeding Disorders Foundation

Hemophilia federation of America logo

Hemophilia Federation of America

World Federation of Hemophilia logo

World Federation of Hemophilia

National organization for rare disorders logo

National Organization for Rare Disorders

The Coalition for Hemophilia B Logo

The Coalition for Hemophilia B

This listing is provided as a resource only and does not constitute an endorsement by Sanofi of any particular organization or its programming. Additional resources on this topic may be available and should be investigated. Sanofi does not review or control the content of non-Sanofi websites.

Ready to enroll in HemAssist?

Get started with support in just a few steps. You can enroll online or download an enrollment form and bring it to your doctor’s office.

Learn how to enroll
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IMPORTANT SAFETY INFORMATION AND INDICATION
INDICATION
IMPORTANT SAFETY INFORMATION
INDICATION

ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein] is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital Factor IX deficiency. Your healthcare provider may give you ALPROLIX when you have surgery.

IMPORTANT SAFETY INFORMATION

Do not use ALPROLIX if you are allergic to ALPROLIX or any of the other ingredients in ALPROLIX.

Tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, supplements, or herbal medicines, have any allergies and all your medical conditions, including if you are pregnant or planning to become pregnant, are breastfeeding, or have been told you have inhibitors (antibodies) to Factor IX.

Common side effects of ALPROLIX include headache, abnormal sensation in the mouth, and pain in your side with blood in your urine, which may be a sign of clot formation in the urinary collecting system.

Allergic reactions may occur with ALPROLIX. Call your healthcare provider or get emergency treatment right away if you have any of the following symptoms: hives, chest tightness, wheezing, difficulty breathing, or swelling of the face.

Redness to the skin at the injection site may also occur.

ALPROLIX may increase the risk of formation of abnormal blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider or seek emergency care if you have symptoms of a possible abnormal blood clot, which may include: chest pain, difficulty breathing, unexpected swelling of an arm or leg with or without pain or tenderness.

Your body can also make antibodies called "inhibitors" against ALPROLIX, which may stop ALPROLIX from working properly.

These are not all of the possible side effects of ALPROLIX. Talk to your healthcare provider right away about any side effect that bothers you or does not go away, or if bleeding is not controlled using ALPROLIX.

© 2025 Sanofi. All rights reserved. ALPROLIX, HemAssist, and Sanofi are trademarks of Sanofi or an affiliate. All other trademarks are the property of their respective owners. MAT-US-2505184-v1.0-08/2025